Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 8/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 8/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 8/20 | 0.49 |
| ▸ | PDE2A | O00408 | 6/20 | 0.49 |
| ▸ | CFTR | P13569 | 2/20 | 0.49 |
| ▸ | PDE5A | O76074 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | PDE6C | P51160 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13111707 | 0.88 | PDE1A (0.49) | PDE1APDE1BPDE1CPDE2ACFTR | |
| SCHEMBL7637587 | 0.83 | PDE1A (0.45) | PDE1APDE1BPDE1CPDE2ACFTR | |
| SCHEMBL7089135 | 0.82 | PDE1A (0.47) | PDE1APDE1BPDE1CPDE2ACFTR | |
| SCHEMBL15168097 | 0.76 | KMT2A (0.45) | PDE1APDE1BPDE1CTSHRALDH1A1 | |
| Isobutylmethylxanthine SCHEMBL1020643 | 0.72 | PDE2A (0.62) | PDE1APDE1BPDE1CPDE2ACFTR | |
| SCHEMBL29015257 | 0.70 | KDM4E (0.34) | PDE1APDE1BPDE1CPDE2ACFTR | |
| SCHEMBL1200300 | 0.70 | ADORA2A (0.68) | PDE1APDE1BPDE1CPDE2ACFTR | |
| SCHEMBL10992924 | 0.70 | PDE1A (0.46) | PDE1APDE1BPDE1CPDE2ACFTR | |
| SCHEMBL11033822 | 0.69 | PDE1A (0.73) | PDE1APDE1BPDE1CPDE2ACFTR | |
| SCHEMBL17682185 | 0.67 | LMNA (0.50) | PDE4AADORA1PDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114894931-A | Detection reagent, detection method and application of guanosine cyclophosphate | 北京豪思生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |