Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | NAT1 | P18440 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814821 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL15816665 | 0.80 | MAOA (0.67) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL20534585 | 0.80 | AKR1B1 (0.71) | MEN1KMT2AMAPTAKR1B1 | |
| SCHEMBL13401689 | 0.80 | AKR1B1 (0.71) | MEN1KMT2AMAPTAKR1B1 | |
| SCHEMBL15816669 | 0.80 | MAOA (0.67) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL15816667 | 0.80 | MAOA (0.67) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL13851456 | 0.80 | AKR1B1 (0.71) | MEN1KMT2AMAPTAKR1B1 | |
| SCHEMBL12712441 | 0.76 | SLC2A1 (0.57) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL2175161 | 0.76 | NAT1 (0.45) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL2175164 | 0.76 | NAT1 (0.45) | MEN1KMT2AMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890963-A | Benzylidene thiazolidinedione derivatives, and preparation method and application thereof | 湖州师范学院 | 2022-08-12 | — | — | CN | disclosed |