Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877230 | 0.94 | CHRM2 (0.51) | CHRM2CHRM3OPRM1SIGMAR1MEN1 | |
| SCHEMBL2874721 | 0.87 | CHRM2 (0.48) | CHRM2CHRM3OPRM1SIGMAR1MEN1 | |
| SCHEMBL2878858 | 0.86 | KDM4E (0.39) | MEN1KMT2A | |
| SCHEMBL2877284 | 0.85 | OPRM1 (0.41) | CHRM2CHRM3OPRM1SIGMAR1DRD2 | |
| SCHEMBL2870899 | 0.85 | KDM4E (0.38) | MEN1KMT2A | |
| SCHEMBL2877227 | 0.85 | CHRM2 (0.52) | CHRM2CHRM3OPRM1SIGMAR1MEN1 | |
| SCHEMBL2876663 | 0.85 | KDM4E (0.38) | MEN1KMT2A | |
| SCHEMBL3807589 | 0.82 | MKNK1 (0.39) | CHRM2CHRM3OPRM1 | |
| SCHEMBL2871311 | 0.82 | OPRM1 (0.38) | CHRM2CHRM3OPRM1 | |
| SCHEMBL2873438 | 0.81 | C5AR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |