Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577032 | 0.86 | IDO1 (0.42) | IDO1TBXAS1HDAC4DYRK1AIMPDH2 | |
| SCHEMBL10249258 | 0.82 | TSHR (0.44) | IDO1TBXAS1HDAC4DYRK1AIMPDH2 | |
| SCHEMBL10192320 | 0.81 | IDO1 (0.39) | IDO1TBXAS1HDAC4DYRK1AIMPDH2 | |
| SCHEMBL28231411 | 0.73 | MAPT (0.43) | IDO1TBXAS1DYRK1AIMPDH2PIM1 | |
| SCHEMBL16646852 | 0.73 | KDM4E (0.44) | IDO1TBXAS1DYRK1AIMPDH2CD38 | |
| SCHEMBL27913317 | 0.72 | HTT (0.41) | IDO1TBXAS1DYRK1AIMPDH2PIM1 | |
| SCHEMBL20150108 | 0.72 | AAK1 (0.37) | IDO1HDAC4IMPDH2AAK1TSHR | |
| SCHEMBL26259995 | 0.70 | TBXAS1 (0.44) | IDO1TBXAS1DYRK1AIMPDH2PIM1 | |
| SCHEMBL26259982 | 0.70 | TBXAS1 (0.47) | IDO1TBXAS1DYRK1AIMPDH2PIM1 | |
| SCHEMBL17643659 | 0.69 | IDO1 (0.42) | IDO1TBXAS1DYRK1AIMPDH2CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103221047-B | Compounds and methods | TEMPERO PHARMACEUTICALS INC | 2014-12-17 | — | — | CN | disclosed |