Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20243512 | 0.74 | CA1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL5257547 | 0.73 | ALDH1A1 (0.40) | GAACYP1A2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1524529 | 0.73 | ALDH1A1 (0.40) | GAACYP1A2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL20240793 | 0.71 | KMT2A (0.44) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL27371945 | 0.70 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL1827489 | 0.70 | — | — | |
| SCHEMBL2397844 | 0.70 | TSHR (0.44) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL27502540 | 0.70 | ALDH1A1 (0.47) | GAACYP1A2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10443538 | 0.69 | PEPD (0.34) | GAACYP1A2ALDH1A1FLT3MAPT | |
| SCHEMBL27585634 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104262328-A | Compound for inhibiting kinase activity of BTK and/or JAK3 | BEIJING HANMI PHARMACEUTICAL CO LTD | 2015-01-07 | — | — | CN | disclosed |