Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.81 |
| ▸ | MEN1 | O00255 | 11/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694084 | 0.92 | DHODH (0.76) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL479877 | 0.89 | DHODH (1.00) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL479805 | 0.86 | DHODH (0.76) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL846930 | 0.86 | DHODH (0.76) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9075528 | 0.85 | MEN1 (1.00) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5217337 | 0.83 | MEN1 (0.75) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7281512 | 0.83 | DHODH (0.71) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28526675 | 0.83 | DHODH (0.71) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14576189 | 0.82 | DHODH (0.69) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13196213 | 0.79 | DHODH (0.66) | DHODHMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334175-A | Alpha 7 nicotinic acetylcholine receptor allosteric modulators, their derivatives and uses thereof | ANVYL LLC | 2015-02-04 | — | — | CN | claimed |
| CN-104334175-A | Alpha 7 nicotinic acetylcholine receptor allosteric modulators, their derivatives and uses thereof | ANVYL LLC | 2015-02-04 | — | — | CN | disclosed |