Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | CTRC | Q99895 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306220 | 0.98 | NPC1 (0.56) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL16716532 | 0.91 | MEN1 (0.66) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL15453227 | 0.91 | MEN1 (0.66) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL29620538 | 0.91 | MEN1 (0.66) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL25298467 | 0.89 | CTRC (0.67) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL12306218 | 0.89 | CTRC (0.67) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL17996251 | 0.89 | CTRC (0.67) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL21689659 | 0.89 | CTRC (0.67) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL19534229 | 0.89 | CTRC (0.67) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL24534378 | 0.89 | CTRC (0.67) | NPC1RAB9AADORA3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103396404-B | Compound using triphenylpyrimidine as core as well as preparation method and application thereof | UNIV SOUTH CHINA TECH | 2015-04-22 | — | — | CN | disclosed |