Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382898 | 0.86 | ESR2 (0.56) | DGAT1MAPT | |
| SCHEMBL382897 | 0.86 | ESR2 (0.56) | DGAT1MAPT | |
| SCHEMBL17327330 | 0.86 | ESR2 (0.56) | DGAT1MAPT | |
| SCHEMBL10197496 | 0.86 | DGAT1 (0.47) | IDO1DGAT1MAPT | |
| SCHEMBL17327303 | 0.85 | DGAT1 (0.51) | DGAT1MAPT | |
| SCHEMBL18763690 | 0.85 | DGAT1 (0.51) | DGAT1MAPT | |
| SCHEMBL28002066 | 0.85 | DGAT1 (0.46) | IDO1DGAT1MAPTSLC6A3 | |
| SCHEMBL1399745 | 0.85 | DGAT1 (0.51) | IDO1DGAT1MAPT | |
| SCHEMBL4673308 | 0.85 | DGAT1 (0.46) | IDO1DGAT1MAPT | |
| SCHEMBL28102455 | 0.85 | DGAT1 (0.46) | IDO1DGAT1MAPTSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104496795-A | Method for preparing DGAT-1 inhibitor intermediate | PORTON FINE CHEMICALS LTD | 2015-04-08 | — | — | CN | disclosed |