Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 7/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | RPS6KA5 | O75582 | 6/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007251 | 1.00 | CDC7 (0.46) | CDC7ENPP3GRM2FFAR4RPS6KA5 | |
| SCHEMBL30750938 | 0.91 | CDC7 (0.46) | CDC7GRM2RPS6KA5CDK2MAP3K14 | |
| SCHEMBL28617905 | 0.79 | RPS6KA5 (0.47) | CDC7RPS6KA5CDK2RPS6KA4 | |
| SCHEMBL29651176 | 0.79 | RPS6KA5 (0.47) | CDC7RPS6KA5CDK2RPS6KA4 | |
| SCHEMBL27253692 | 0.77 | RPS6KA5 (0.41) | RPS6KA5RPS6KA4 | |
| SCHEMBL17682937 | 0.76 | GRM2 (0.36) | GRM2TRPV4PSEN1PSEN2APH1B | |
| SCHEMBL19540762 | 0.73 | RARG (0.37) | GRM2TRPV4PSEN1PSEN2APH1B | |
| SCHEMBL19254673 | 0.73 | GRM2 (0.36) | GRM2CDK2TRPV4PSEN1PSEN2 | |
| SCHEMBL30394203 | 0.73 | ENPP3 (0.48) | CDC7ENPP3GRM2FFAR4CDK2 | |
| SCHEMBL27400872 | 0.73 | ENPP3 (0.48) | CDC7ENPP3GRM2FFAR4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907407-A | Inhibitors of cyclin dependent kinase 7(CDK7) | 江苏先声药业有限公司 | 2022-08-16 | — | — | CN | disclosed |