Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 16/20 | 0.71 |
| ▸ | CDK12 | Q9NYV4 | 16/20 | 0.71 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.71 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.71 |
| ▸ | CDK2 | P24941 | 13/20 | 0.71 |
| ▸ | CDK9 | P50750 | 13/20 | 0.71 |
| ▸ | CDK7 | P50613 | 13/20 | 0.71 |
| ▸ | CCNH | P51946 | 13/20 | 0.71 |
| ▸ | MNAT1 | P51948 | 9/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29850286 | 1.00 | CCNK (0.71) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL29850496 | 1.00 | CCNK (0.71) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL28817405 | 1.00 | CCNK (0.71) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24589005 | 0.92 | CCNK (0.72) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184374 | 0.92 | CCNK (0.78) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24588868 | 0.91 | CCNK (0.71) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24588867 | 0.91 | CCNK (0.71) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL29492506 | 0.91 | CCNK (0.71) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL29498458 | 0.91 | CCNK (0.69) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL26327191 | 0.90 | CCNK (0.68) | CCNKCDK12CCNT1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907406-A | Pyrimidine derivative, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-08-16 | — | — | CN | disclosed |