Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.52 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.48 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362785 | 0.92 | MOGAT2 (0.56) | MOGAT2MGAT2PLK4MEN1KMT2A | |
| SCHEMBL5358368 | 0.87 | MOGAT2 (0.61) | MOGAT2MGAT2LRRK2MEN1KMT2A | |
| SCHEMBL5363186 | 0.86 | MOGAT2 (0.54) | MOGAT2MGAT2PLK4PRKDCMEN1 | |
| SCHEMBL7137576 | 0.85 | MOGAT2 (0.57) | MOGAT2MGAT2PRKDCLRRK2MEN1 | |
| SCHEMBL7140002 | 0.84 | MOGAT2 (0.56) | MOGAT2MGAT2PRKDCPSEN1PSEN2 | |
| SCHEMBL5357745 | 0.84 | MOGAT2 (0.58) | MOGAT2MGAT2PRKDCLRRK2 | |
| SCHEMBL7139561 | 0.83 | MOGAT2 (0.56) | MOGAT2MGAT2MAP1LC3BRAF1PRKDC | |
| SCHEMBL5361605 | 0.83 | MAP1LC3B (0.57) | MOGAT2MGAT2MAP1LC3BRAF1PLK4 | |
| SCHEMBL5370221 | 0.83 | MOGAT2 (0.57) | MOGAT2MGAT2MEN1KMT2A | |
| SCHEMBL5362279 | 0.83 | MOGAT2 (0.57) | MOGAT2MGAT2PRKDCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104326964-A | Fluoro2-indolone derivatives and preparation and application thereof | INST OCEANOLOGY CHINESE ACAD | 2015-02-04 | — | — | CN | claimed |
| CN-104326964-A | Fluoro2-indolone derivatives and preparation and application thereof | INST OCEANOLOGY CHINESE ACAD | 2015-02-04 | — | — | CN | disclosed |