Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448143 | 0.85 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL9329307 | 0.81 | TDP1 (0.39) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL7531460 | 0.80 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL381504 | 0.79 | TDP1 (0.46) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL31325517 | 0.77 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL10713130 | 0.77 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL17529908 | 0.77 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL9294360 | 0.77 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| Bromide SCHEMBL11384376 | 0.77 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11387157 | 0.75 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354886-B1 | Process for the preparation of tertiary phosphines | SALTIGO GMBH (DE) | 2009-08-26 | — | — | EP | claimed |
| US-7230136-B2 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2007-06-12 | — | — | US | claimed |
| US-20030229240-A1 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | US | claimed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | claimed |
| US-7847126-B2 | prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example | LANXESS DEUTSCHLAND GMBH (DE) | 2010-12-07 | — | — | US | disclosed |
| EP-1354886-B1 | Process for the preparation of tertiary phosphines | SALTIGO GMBH (DE) | 2009-08-26 | — | — | EP | disclosed |
| US-20070299273-A1 | prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example | LANXESS DEUTSCHLAND GMBH (DE) | 2007-12-27 | — | — | US | disclosed |
| US-7230136-B2 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2007-06-12 | — | — | US | disclosed |
| US-20030229240-A1 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | US | disclosed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | disclosed |
| EP-0122587-B1 | PROCESS FOR PREPARING ORGANIC CHLOROPHOSPHANES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-04-20 | — | — | EP | disclosed |
| US-4632995-A | Process for the preparation of phenyl- and thienyl-chlorophosphane derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-12-30 | — | — | US | disclosed |
| EP-0122587-A2 | Process for preparing organic chlorophosphanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-24 | — | — | EP | disclosed |