Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327624 | 0.82 | TDP1 (0.39) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL5448143 | 0.81 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL2881810 | 0.81 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL381504 | 0.75 | TDP1 (0.46) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL29274146 | 0.75 | TDP1 (0.34) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL9327675 | 0.73 | CYP3A4 (0.38) | CYP3A4 | |
| SCHEMBL17529908 | 0.73 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL31325517 | 0.73 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| Bromide SCHEMBL11384376 | 0.73 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL9294360 | 0.73 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283350-A | Aryl esters of phosphonous halides and a process for the preparation thereof | HOECHST AKTIENGESELLSHAFT (DE) | 1994-02-01 | — | — | US | disclosed |