SCHEMBL28818207

SCHEMBL28818207

CN1CCC[C@@]1(OCc1ccccc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.41
OPRD1 P41143 1/20 0.41
OPRK1 P41145 1/20 0.41
OPRL1 P41146 1/20 0.41
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28852199 1.00 OPRM1 (0.41) OPRM1OPRD1OPRK1OPRL1ALDH1A1
SCHEMBL8821789 0.81 MEN1 (0.46)
SCHEMBL25051426 0.78 OPRM1 (0.39) OPRM1OPRD1OPRK1OPRL1
SCHEMBL6129775 0.78 OPRM1 (0.39) OPRM1OPRD1OPRK1OPRL1
SCHEMBL7478810 0.75
SCHEMBL19968196 0.74
SCHEMBL7798750 0.74
SCHEMBL3578384 0.74
SCHEMBL28519268 0.74 HCRTR1 (0.41)
SCHEMBL28225504 0.73 CYP2D6 (0.43) OPRM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114933511-B Method for quickly converting carboxyl into aldehyde group 中国科学院兰州化学物理研究所 2023-02-24 CN disclosed
CN-114933511-A Method for quickly converting carboxyl into aldehyde group 中国科学院兰州化学物理研究所 2022-08-23 CN disclosed