Butadiene

Butadiene

SCHEMBL28818231

C=CC(=C)C.C=CC=C.C=Cc1ccc(C)cc1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
ALDH1A1 P00352 3/20 0.46
TP53 P04637 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
TSHR P16473 2/20 0.42
CYP2A6 P11509 1/20 0.38
TGM2 P21980 1/20 0.37
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPT P10636 3/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
RECQL P46063 1/20 0.36
MDM2 Q00987 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11325348 0.96 ALDH1A1 (0.50) CYP3A4CYP2C9CYP2C19ALDH1A1TP53
SCHEMBL7672210 0.96 ALDH1A1 (0.50) CYP3A4CYP2C9CYP2C19ALDH1A1TP53
SCHEMBL2849520 0.94 CYP3A4 (0.48) CYP3A4CYP2C9CYP2C19ALDH1A1TP53
Styrene SCHEMBL27178250 0.93 ALDH1A1 (0.50) CYP3A4CYP2C9CYP2C19ALDH1A1TP53
Styrene SCHEMBL11203687 0.88 ALDH1A1 (0.54) CYP3A4CYP2C9CYP2C19ALDH1A1TP53
SCHEMBL123485 0.87 ALDH1A1 (0.55) CYP3A4CYP2C9CYP2C19ALDH1A1TP53
SCHEMBL8520742 0.87 ALDH1A1 (0.61) CYP3A4CYP2C9CYP2C19ALDH1A1TP53
Butadiene SCHEMBL5137794 0.87 ALDH1A1 (0.61) CYP3A4CYP2C9CYP2C19ALDH1A1TP53
SCHEMBL14911 0.82
SCHEMBL679555 0.82 ALDH1A1 (0.69) CYP3A4CYP2C9CYP2C19ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104619731-A Paramethylstyrene block copolymers and their use KRATON POLYMERS US LLC 2015-05-13 CN disclosed