Sugi Predict

Sugi Predict / Compounds / Pyrogallol

Pyrogallol

Pyrogallol

SCHEMBL2881879

COc1ccc(S(=O)(=O)O)cc1.COc1ccc(S(=O)(=O)O)cc1.COc1ccc(S(=O)(=O)O)cc1.Oc1cccc(O)c1O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 4/20 0.51
▸ GAA P10253 2/20 0.51
▸ RELA Q04206 1/20 0.47
▸ PTGS2 P35354 1/20 0.47
▸ CA1 P00915 3/20 0.47
▸ CA2 P00918 3/20 0.47
▸ MMP2 P08253 2/20 0.47
▸ MMP9 P14780 2/20 0.47
▸ MMP1 P03956 1/20 0.47
▸ MMP8 P22894 1/20 0.47
▸ MMP13 P45452 1/20 0.47
▸ NPC1 O15118 1/20 0.46
▸ PKLR P30613 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ LMNA P02545 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ TP53 P04637 2/20 0.46
▸ MAPT P10636 2/20 0.46
▸ HPGD P15428 2/20 0.46
▸ ALOX15 P16050 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrogallol SCHEMBL5360986 1.00 PKM (0.51) PKMGAARELAPTGS2CA1
SCHEMBL286762 0.85 PKM (0.67) PKMGAAPTGS2CA1CA2
Hydrochloric Acid SCHEMBL1328452 0.83 PKM (0.64) PKMGAAPTGS2CA1CA2
Fluoride SCHEMBL27786941 0.83 PKM (0.64) PKMGAACA1CA2MMP2
Water SCHEMBL8627002 0.83 PKM (0.64) PKMGAAPTGS2CA1CA2
Ammonia Solution, Strong SCHEMBL25386463 0.83 PKM (0.64) PKMGAAPTGS2CA1CA2
Hydrogen Sulfide SCHEMBL27655402 0.83 PKM (0.64) PKMGAAPTGS2CA1CA2
SCHEMBL10497952 0.83 PKM (0.64) PKMGAAPTGS2CA1CA2
SCHEMBL8627561 0.83 PKM (0.64) PKMGAAPTGS2CA1CA2
SCHEMBL8154133 0.82 TSHR (0.64) PKMGAACA1CA2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1951801-B1 IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2013-01-02 — — EP claimed
EP-1951801-A2 IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM General Electric Company (US) 2008-08-06 — — EP claimed
WO-2007053311-A2 IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-05-10 — — WO claimed
US-20070100038-A1 Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) 2007-05-03 — — US claimed
EP-1951801-B1 IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2013-01-02 — — EP disclosed
US-7812078-B2 Blend of an uncappped polycarbonate and an arylcarboxylate-endcapped homo-or copolycarbonate that is prepared by interfacial polymerization of diol, activated carbonyl compound and an arylcarbonyl halide; decreased discoloration after exposure to gamma radiation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-10-12 — — US disclosed
EP-1951801-A2 IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM General Electric Company (US) 2008-08-06 — — EP disclosed
WO-2007053311-A2 IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-05-10 — — WO disclosed
US-20070100038-A1 Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) 2007-05-03 — — US disclosed