SCHEMBL28819293

SCHEMBL28819293

Cc1cccc(C)c1C(=O)C[PH](=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
ERCC5 P28715 1/20 0.38
FEN1 P39748 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
MYC P01106 1/20 0.35
RAB9A P51151 2/20 0.35
HPGD P15428 4/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
PTGS2 P35354 1/20 0.33
FABP3 P05413 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12520365 0.73 SMN1; SMN2 (0.35) GPR52L3MBTL1ERCC5FEN1TDP1
SCHEMBL27822952 0.73 AKR1B1 (0.41) TDP1SMN1; SMN2HPGDALDH1A1KDM4E
SCHEMBL1830537 0.73 L3MBTL1 (0.40) GPR52L3MBTL1TDP1SMN1; SMN2MYC
SCHEMBL28815060 0.71 KMT2A (0.38) L3MBTL1SMN1; SMN2RAB9AHPGDALDH1A1
SCHEMBL17111287 0.69 MEN1 (0.45) GPR52L3MBTL1ERCC5FEN1TDP1
SCHEMBL16581126 0.69 L3MBTL1 (0.41) GPR52L3MBTL1ERCC5FEN1TDP1
SCHEMBL9356347 0.68 NR4A2 (0.52) L3MBTL1TDP1SMN1; SMN2RAB9AHPGD
SCHEMBL5725592 0.67 GSK3B (0.48) GPR52L3MBTL1ERCC5FEN1TDP1
SCHEMBL27573915 0.67 L3MBTL1 (0.40) GPR52L3MBTL1ERCC5FEN1TDP1
SCHEMBL12483502 0.67 TAAR1 (0.41) SMN1; SMN2HPGDALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104603217-B UV-curable coating compositions and methods for using the same PPG涂料(天津)有限公司 2017-01-18 CN disclosed
CN-104603217-A UV-curable coating compositions and methods for using the same PPG COATINGS TIANJIN CO LTD 2015-05-06 CN disclosed