Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422284 | 1.00 | CA1 (0.61) | CA1CA2CA12CA9NNMT | |
| Hydrochloric Acid SCHEMBL29969325 | 0.98 | CA1 (0.60) | CA1CA2CA12CA9NNMT | |
| SCHEMBL1422276 | 0.86 | CA2 (0.72) | CA1CA2CA12CA9KCNH2 | |
| SCHEMBL1688213 | 0.82 | KCNH2 (0.56) | CA1CA2NNMTKCNH2MKNK1 | |
| SCHEMBL30269658 | 0.81 | CA1 (0.47) | CA1CA2NNMTKCNH2MKNK1 | |
| SCHEMBL2120289 | 0.81 | KDM4E (0.53) | CA1CA2NNMTKCNH2MKNK1 | |
| SCHEMBL3511652 | 0.81 | CA1 (0.47) | CA1CA2CA12CA9NNMT | |
| SCHEMBL119737 | 0.81 | CA1 (0.47) | CA1CA2NNMTKCNH2MKNK1 | |
| SCHEMBL28016001 | 0.81 | CA1 (0.47) | CA1CA2NNMTKCNH2MKNK1 | |
| SCHEMBL24010110 | 0.79 | KCNH2 (0.47) | CA1CA2NNMTKCNH2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102099036-B | Compounds and methods for treating inflammatory and fibrotic conditions | INTERMUNE INC | 2015-05-27 | — | — | CN | disclosed |