SCHEMBL28819441

SCHEMBL28819441

NC(Cc1ccccc1)(c1ccccc1)C(N)(Cc1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.56
TAAR1 Q96RJ0 1/20 0.56
CYP1A2 P05177 2/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.50
HIF1A Q16665 1/20 0.50
KCNN4 O15554 1/20 0.48
KIF11 P52732 5/20 0.47
LOXL2 Q9Y4K0 1/20 0.42
LMNA P02545 1/20 0.41
CYP2D6 P10635 1/20 0.41
KCNA5 P22460 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
CYP3A4 P08684 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4972631 0.89 SLC6A2 (0.50) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL5402199 0.87 SLC6A2 (0.48) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL2573964 0.82 TAAR1 (0.58) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
Phosphine SCHEMBL28505016 0.80 SLC6A2 (0.56) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL759856 0.80 SLC6A2 (0.56) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
Bromide SCHEMBL28902281 0.80 SLC6A2 (0.56) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL2406230 0.80 SLC6A2 (0.56) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
Water SCHEMBL11128724 0.80 SLC6A2 (0.56) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL11784213 0.80 SLC6A2 (0.56) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19
SCHEMBL10503241 0.78 TAAR1 (0.67) SLC6A2TAAR1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773400-B Rhodium complex, preparation method, intermediate and application thereof 中国科学院上海有机化学研究所 2024-04-26 CN disclosed
CN-114773400-A Rhodium complex, preparation method, intermediate and application thereof 中国科学院上海有机化学研究所 2022-07-22 CN disclosed