SCHEMBL28819474

SCHEMBL28819474

CCCCCCCCCCCCCCCC=Cc1cc(O)ccc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.48
MAPT P10636 3/20 0.46
MEN1 O00255 2/20 0.46
TP53 P04637 2/20 0.46
ALOX15 P16050 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP3A4 P08684 1/20 0.46
ALOX5 P09917 1/20 0.46
TYR P14679 1/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PSMB11 A5LHX3 2/20 0.43
PSMA7 O14818 2/20 0.43
PSMB1 P20618 2/20 0.43
PSMA1 P25786 2/20 0.43
PSMA2 P25787 2/20 0.43
PSMA3 P25788 2/20 0.43
PSMA4 P25789 2/20 0.43
PSMB8 P28062 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30792609 1.00 APP (0.48) APPMAPTMEN1TP53ALOX15
SCHEMBL28819473 1.00 APP (0.48) APPMAPTMEN1TP53ALOX15
SCHEMBL5802799 0.93 APP (0.50) APPMAPTMEN1TP53ALOX15
SCHEMBL5802798 0.93 APP (0.50) APPMAPTMEN1TP53ALOX15
SCHEMBL23203379 0.88 APP (0.44) APPMAPTMEN1TP53ALOX15
SCHEMBL28810990 0.87 TYR (0.50) MAPTMEN1TP53ALOX15KMT2A
SCHEMBL19668035 0.87 TYR (0.50) MAPTMEN1TP53ALOX15KMT2A
SCHEMBL9473131 0.81 ALDH1A1 (0.45) APPMAPTMEN1TP53ALOX15
SCHEMBL30585894 0.81 F7 (0.46) MAPTTP53ALOX15TSHRKDM4E
SCHEMBL1072894 0.80 CYSLTR2 (0.50) MAPTALOX15KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114641272-B Skin lightening compositions 贝雅欧若拉实验室公司 2024-06-04 CN disclosed
CN-114641272-A Skin lightening compositions 贝雅欧若拉实验室公司 2022-06-17 CN disclosed