Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819671 | 0.87 | KDM4E (0.44) | PTAFRMAPTALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL28819516 | 0.87 | PTAFR (0.47) | PTAFRMAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28819553 | 0.87 | PTAFR (0.45) | PTAFRMAPTTP53TSHRLMNA | |
| SCHEMBL28819533 | 0.86 | PTAFR (0.44) | PTAFRMAPTPOLBTSHR | |
| SCHEMBL27747026 | 0.86 | MEN1 (0.45) | PTAFRMAPTPOLBTSHR | |
| Hydrochloric Acid SCHEMBL27747036 | 0.85 | MEN1 (0.44) | PTAFRMAPTPOLBTSHR | |
| SCHEMBL28077564 | 0.85 | MEN1 (0.43) | PTAFRMAPTTSHRLMNA | |
| SCHEMBL28819640 | 0.84 | NPSR1 (0.54) | PTAFRMAPTTSHRLMNA | |
| SCHEMBL3561095 | 0.84 | TSHR (0.43) | PTAFRMAPTPOLBTSHR | |
| SCHEMBL28819621 | 0.84 | PTAFR (0.49) | PTAFRMAPTALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |