Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819617 | 0.92 | HTT (0.45) | NPSR1LMNAKDM4EHTTMCHR1 | |
| SCHEMBL28819671 | 0.90 | KDM4E (0.44) | NPSR1LMNAKDM4EHTTPTAFR | |
| SCHEMBL28819615 | 0.89 | CTSD (0.49) | NPSR1LMNAKDM4EHTTPTAFR | |
| SCHEMBL28819512 | 0.89 | CTSD (0.47) | NPSR1LMNAKDM4EHTTPTAFR | |
| SCHEMBL28819650 | 0.87 | CYP2D6 (0.42) | NPSR1LMNAKDM4EHTTPTAFR | |
| SCHEMBL28819578 | 0.86 | PTAFR (0.40) | NPSR1LMNAKDM4EHTTPTAFR | |
| SCHEMBL28819537 | 0.85 | KDM4E (0.44) | KDM4EHTTPTAFRMAPTCTSD | |
| SCHEMBL28819557 | 0.84 | PTAFR (0.46) | LMNAPTAFRTSHRMAPT | |
| SCHEMBL28077564 | 0.84 | MEN1 (0.43) | LMNAKDM4EHTTPTAFRTSHR | |
| SCHEMBL28819553 | 0.84 | PTAFR (0.45) | LMNAPTAFRTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |