Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 6/20 | 0.45 |
| ▸ | PTAFR | P25105 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819694 | 0.91 | KDM4E (0.43) | KDM4EHSD17B10BRD4PTAFRMAPT | |
| SCHEMBL28819509 | 0.91 | KDM4E (0.43) | KDM4EHSD17B10BRD4PTAFRMAPT | |
| SCHEMBL28819718 | 0.89 | KDM4E (0.48) | KDM4EHSD17B10TP53BRD4PTAFR | |
| SCHEMBL28948657 | 0.89 | KDM4E (0.48) | KDM4EHSD17B10TP53PTAFRMAPT | |
| SCHEMBL16569243 | 0.89 | TP53 (0.51) | KDM4EHSD17B10TP53PTAFRMAPT | |
| SCHEMBL27747028 | 0.89 | KDM4E (0.46) | KDM4EHSD17B10PTAFRMAPTHTT | |
| SCHEMBL28819753 | 0.88 | KDM4E (0.46) | KDM4EHSD17B10TP53BRD4PTAFR | |
| SCHEMBL28819670 | 0.87 | HSD17B10 (0.61) | KDM4EHSD17B10TP53PTAFRMAPT | |
| SCHEMBL28819529 | 0.87 | MCHR1 (0.47) | KDM4EHSD17B10TP53PTAFRMAPT | |
| SCHEMBL28819674 | 0.87 | MCHR1 (0.47) | KDM4EHSD17B10PTAFRHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |