Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | PDE6D | O43924 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819659 | 0.91 | PIN1 (0.52) | HSD17B10KDM4ETSHRLMNAMEN1 | |
| SCHEMBL28948669 | 0.90 | KDM4E (0.49) | HSD17B10KDM4ETSHRLMNAMEN1 | |
| SCHEMBL16569243 | 0.90 | TP53 (0.51) | HSD17B10KDM4ETSHRLMNAALDH1A1 | |
| SCHEMBL28819621 | 0.89 | PTAFR (0.49) | HSD17B10KDM4ETSHRLMNAMEN1 | |
| SCHEMBL28819587 | 0.89 | KDM4E (0.48) | HSD17B10KDM4ETSHRMEN1KMT2A | |
| SCHEMBL28819716 | 0.88 | ALDH1A1 (0.47) | HSD17B10KDM4ETSHRLMNAMEN1 | |
| SCHEMBL28819741 | 0.88 | KDM4E (0.47) | HSD17B10KDM4ETSHRLMNAMEN1 | |
| SCHEMBL28819490 | 0.88 | KDM4E (0.47) | HSD17B10KDM4ETSHRLMNAMEN1 | |
| SCHEMBL28819667 | 0.88 | KDM4E (0.47) | HSD17B10KDM4ETSHRMEN1KMT2A | |
| SCHEMBL28819565 | 0.88 | HSD17B10 (0.47) | HSD17B10KDM4ETSHRLMNAPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |