Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819529 | 0.91 | MCHR1 (0.47) | KDM4EHSD17B10PTAFRMCHR1TSHR | |
| SCHEMBL28819509 | 0.89 | KDM4E (0.43) | KDM4EHSD17B10PTAFRMCHR1TSHR | |
| SCHEMBL28819694 | 0.87 | KDM4E (0.43) | KDM4EHSD17B10PTAFRMCHR1MAPT | |
| SCHEMBL28819587 | 0.85 | KDM4E (0.48) | KDM4EHSD17B10PTAFRMCHR1TSHR | |
| SCHEMBL28819547 | 0.85 | KDM4E (0.47) | KDM4EHSD17B10PTAFRMCHR1HTT | |
| SCHEMBL28819667 | 0.85 | KDM4E (0.47) | KDM4EHSD17B10PTAFRMCHR1TSHR | |
| SCHEMBL28819565 | 0.85 | HSD17B10 (0.47) | KDM4EHSD17B10PTAFRTSHRMAPT | |
| SCHEMBL28819535 | 0.84 | KDM4E (0.46) | KDM4EHSD17B10PTAFRTSHRHTT | |
| SCHEMBL27747028 | 0.84 | KDM4E (0.46) | KDM4EHSD17B10PTAFRTSHRHTT | |
| SCHEMBL28819624 | 0.84 | KDM4E (0.46) | KDM4EHSD17B10PTAFRTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |