Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 5/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819511 | 0.92 | OPRM1 (0.39) | OPRM1OPRL1OPRK1OGFRL1OPRD1 | |
| SCHEMBL28819530 | 0.92 | MCHR1 (0.44) | OPRM1OPRL1OPRK1OGFRL1OPRD1 | |
| SCHEMBL28819625 | 0.91 | OPRM1 (0.41) | OPRM1OPRL1OPRK1OGFRL1OPRD1 | |
| SCHEMBL28819551 | 0.87 | KDM4E (0.41) | OPRM1OPRK1OGFRL1OPRD1MCHR1 | |
| SCHEMBL28819629 | 0.87 | CYP3A4 (0.39) | OPRM1OPRL1OPRK1OGFRL1OPRD1 | |
| SCHEMBL28819721 | 0.87 | KDM4E (0.42) | OPRM1OPRK1OGFRL1OPRD1BRD4 | |
| SCHEMBL28819567 | 0.86 | HDAC1 (0.43) | OPRM1OPRL1OPRK1OGFRL1OPRD1 | |
| SCHEMBL28819538 | 0.86 | OPRM1 (0.40) | OPRM1OPRL1OPRK1OGFRL1OPRD1 | |
| SCHEMBL16569242 | 0.86 | HDAC1 (0.44) | OPRM1OPRL1OPRK1OGFRL1OPRD1 | |
| SCHEMBL28819675 | 0.84 | MCHR1 (0.44) | OPRM1OPRL1OPRK1OGFRL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |