Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane Carboxamide SCHEMBL28819590 | 0.91 | NR1H4 (0.49) | NR1H4OPRM1OPRD1OPRK1OGFRL1 | |
| Cyclohexane Carboxamide SCHEMBL28819506 | 0.90 | NR1H4 (0.49) | NR1H4OPRM1OPRD1OPRK1OGFRL1 | |
| Cyclohexane Carboxamide SCHEMBL28819682 | 0.90 | NR1H4 (0.49) | NR1H4OPRM1OPRD1OPRK1OGFRL1 | |
| Cyclohexane Carboxamide SCHEMBL28819548 | 0.88 | NR1H4 (0.45) | NR1H4OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL29880939 | 0.88 | MAPK10 (0.48) | NR1H4MAPK10HDAC1HDAC8HDAC6 | |
| Cyclohexane Carboxamide SCHEMBL28819715 | 0.88 | NR1H4 (0.49) | NR1H4OPRM1OPRD1OPRK1OGFRL1 | |
| Cyclohexane Carboxamide SCHEMBL28819611 | 0.87 | NR1H4 (0.59) | NR1H4 | |
| Cyclohexane Carboxamide SCHEMBL28948660 | 0.86 | NR1H4 (0.48) | NR1H4OPRM1OPRD1OPRK1OGFRL1 | |
| Cyclohexane Carboxamide SCHEMBL28819483 | 0.86 | NR1H4 (0.48) | NR1H4OPRM1OPRD1OPRK1OGFRL1 | |
| Cyclohexane Carboxamide SCHEMBL28819581 | 0.85 | OPRM1 (0.44) | NR1H4OPRM1OPRD1OPRK1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |