Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 7/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15633341 | 0.86 | TIPARP (0.40) | TIPARPIDO1ARNOTUMPRMT5 | |
| SCHEMBL30859999 | 0.83 | TIPARP (0.44) | TIPARPIDO1ARNOTUMALDH1A1 | |
| SCHEMBL30859849 | 0.79 | TIPARP (0.40) | TIPARPIDO1ARNOTUMPRMT5 | |
| SCHEMBL24968908 | 0.75 | TIPARP (0.43) | TIPARPIDO1AR | |
| SCHEMBL30851298 | 0.74 | TIPARP (0.42) | TIPARPIDO1ARNOTUMPRMT5 | |
| SCHEMBL30507321 | 0.74 | TIPARP (0.43) | TIPARPIDO1NOTUMPRMT5WDR77 | |
| SCHEMBL31464989 | 0.73 | NOTUM (0.40) | TIPARPIDO1ARNOTUMPRMT5 | |
| SCHEMBL24739044 | 0.69 | NOTUM (0.40) | ARNOTUMALDH1A1GAA | |
| SCHEMBL15633366 | 0.69 | NOTUM (0.43) | TIPARPARNOTUMPRMT5WDR77 | |
| SCHEMBL24739443 | 0.69 | BACE1 (0.37) | TIPARPARNOTUMPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822670-A | 5-phenoxy-3h-pyrimidin-4-one derivatives and their use as HIV reverse transcriptase inhibitors | MERCK SHARP & DOHME | 2015-08-05 | — | — | CN | disclosed |