SCHEMBL28820041

SCHEMBL28820041

OB(O)Oc1cccc2c1ccc1cc3ccccc3cc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
HSD17B10 Q99714 4/20 0.42
HIF1A Q16665 1/20 0.42
CYP1B1 Q16678 1/20 0.42
CYP1A2 P05177 3/20 0.41
HPGD P15428 2/20 0.41
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40
AHR P35869 1/20 0.40
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
GAA P10253 4/20 0.37
KDM4E B2RXH2 2/20 0.37
RCE1 Q9Y256 1/20 0.37
HPRT1 P00492 1/20 0.36
TRPM4 Q8TD43 1/20 0.35
THRB P10828 1/20 0.34
NQO1 P15559 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4861556 0.88 ALDH1A1 (0.42) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL29634612 0.88 ALDH1A1 (0.42) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL30960875 0.86 HPRT1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
Fluoride SCHEMBL27490468 0.86 ALDH1A1 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL28700593 0.86 ALDH1A1 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL7611626 0.86 HPRT1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL27810887 0.85 ALDH1A1 (0.40) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
Lithium Ion SCHEMBL31683852 0.83 ALDH1A1 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
SCHEMBL19259375 0.82 CYP1A2 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2
Hydrogen Sulfide SCHEMBL17372873 0.81 CYP1A2 (0.40) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105051620-A Security element having volume hologram and printed feature BAYER MATERIALSCIENCE AG 2015-11-11 CN disclosed