Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.61 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.61 |
| ▸ | CLK1 | P49759 | 1/20 | 0.61 |
| ▸ | CLK2 | P49760 | 1/20 | 0.61 |
| ▸ | CLK3 | P49761 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.61 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.61 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.61 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.61 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | CDK2 | P24941 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8266373 | 0.84 | FGFR1 (0.70) | FGFR1DYRK3CLK1CLK2CLK3 | |
| Indazole SCHEMBL7371212 | 0.79 | HSP90AA1 (0.95) | FGFR1DYRK3CLK1CLK2CLK3 | |
| Indazole SCHEMBL27944553 | 0.78 | HSP90AA1 (0.54) | FGFR1DYRK3CLK1CLK2CLK3 | |
| Indazole SCHEMBL27558509 | 0.77 | HSP90AA1 (0.91) | FGFR1DYRK3CLK1CLK2CLK3 | |
| Indazole SCHEMBL1221882 | 0.77 | HSP90AA1 (1.00) | FGFR1DYRK3CLK1CLK2CLK3 | |
| Indazole SCHEMBL6295 | 0.77 | — | — | |
| Indazole SCHEMBL29355507 | 0.77 | — | — | |
| SCHEMBL2455100 | 0.76 | GSK3B (1.00) | FGFR1DYRK3CLK1CLK2CLK3 | |
| SCHEMBL2460902 | 0.76 | FGFR1 (1.00) | FGFR1DYRK3CLK1CLK2CLK3 | |
| Anthracene SCHEMBL15271626 | 0.75 | HSP90AA1 (0.86) | FGFR1DYRK3CLK1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725319-A | 1H-indazole-3-aminobphenyl urea compound with anti-tumor activity as well as preparation method and application of 1H-indazole-3-aminobphenyl urea compound | UNIV XI AN JIAOTONG | 2015-06-24 | — | — | CN | disclosed |