Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798901 | 0.86 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NCOR2SSTR4 | |
| SCHEMBL1800104 | 0.86 | HDAC1 (0.44) | HDAC1HDAC3HDAC2NCOR2SSTR4 | |
| SCHEMBL1799805 | 0.85 | HDAC1 (0.51) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL17393769 | 0.84 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NCOR2SSTR4 | |
| SCHEMBL3141997 | 0.84 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NCOR2SSTR4 | |
| SCHEMBL9060170 | 0.84 | HDAC1 (0.60) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL9295963 | 0.84 | HDAC1 (0.46) | HDAC1HDAC3HDAC2NCOR2SSTR4 | |
| SCHEMBL9295960 | 0.82 | HDAC1 (0.47) | HDAC1HDAC3HDAC2NCOR2SSTR4 | |
| SCHEMBL7655742 | 0.82 | HDAC1 (0.47) | HDAC1HDAC3HDAC2NCOR2SSTR4 | |
| SCHEMBL1802560 | 0.81 | SSTR4 (0.43) | HDAC1HDAC3HDAC2NCOR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | MSD K.K. (JP) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | NPY1R, MC5R, MC1R | HDAC1 2591/4885HDAC3 2133/4885HDAC2 3451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.