Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 12/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121958 | 0.86 | POLB (0.76) | POLBTDP1TSHRTRPM8LMNA | |
| SCHEMBL6122896 | 0.86 | POLB (0.76) | POLBTDP1TSHRTRPM8LMNA | |
| SCHEMBL6121430 | 0.85 | POLB (0.78) | POLBTDP1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL6122368 | 0.82 | POLB (0.66) | POLBTDP1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL6122020 | 0.82 | POLB (0.78) | POLBTDP1TSHRTRPM8LMNA | |
| SCHEMBL6122800 | 0.79 | POLB (0.69) | POLBTDP1TSHRTRPM8LMNA | |
| SCHEMBL21114755 | 0.79 | TSHR (0.45) | POLBTDP1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL21114756 | 0.79 | TSHR (0.45) | POLBTDP1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL7662082 | 0.79 | SMN1; SMN2 (0.71) | POLBTSHRL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6122191 | 0.78 | POLB (0.68) | POLBTDP1TSHRALDH1A1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107820429-B | Novel compositions and methods for immunotherapy comprising small molecule integrin receptor-ligand agonist adjuvants | 7山药物有限责任公司 | 2022-08-16 | — | — | CN | disclosed |