Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114755 | 1.00 | TSHR (0.45) | TSHRPOLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21114801 | 0.84 | TSHR (0.42) | TSHRPOLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21114800 | 0.84 | TSHR (0.42) | TSHRPOLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6121689 | 0.83 | TSHR (0.41) | TSHRPOLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6122175 | 0.81 | POLB (0.47) | TSHRPOLBALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6122884 | 0.81 | POLB (0.47) | TSHRPOLBALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6123150 | 0.81 | POLB (0.47) | TSHRPOLBALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6122234 | 0.79 | ALDH1A1 (0.40) | TSHRPOLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28820428 | 0.79 | POLB (0.58) | TSHRPOLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6123009 | 0.79 | POLB (0.45) | TSHRPOLBALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190210992-A1 | AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS | TEXAS HEART INSTITUTE (US) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190210992-A1 | AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS | ITGB7, ITGAL, ITGB1 | TSHR 430/4885POLB 4239/4885L3MBTL1 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.