SCHEMBL28822709

SCHEMBL28822709

CCN(CC)c1ncc(B2OC(C)(C)C(C)(C)O2)cn1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ LPL P06858 10/20 0.41
▸ LIPG Q9Y5X9 10/20 0.41
▸ FFAR1 O14842 1/20 0.38
▸ DGAT1 O75907 2/20 0.36
▸ GSK3A P49840 1/20 0.36
▸ GSK3B P49841 1/20 0.36
▸ AAK1 Q2M2I8 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ F11 P03951 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31217291 0.88 LPL (0.42) LPLLIPGFFAR1DGAT1GSK3A
SCHEMBL31217403 0.88 FFAR1 (0.36) LPLLIPGFFAR1DGAT1GSK3A
SCHEMBL31212564 0.85 LPL (0.40) LPLLIPGFFAR1DGAT1GSK3A
SCHEMBL31217264 0.84 LPL (0.44) LPLLIPGFFAR1DGAT1GSK3A
SCHEMBL31217222 0.82 FFAR1 (0.38) LPLLIPGFFAR1DGAT1GSK3A
SCHEMBL31217161 0.82 AAK1 (0.39) LPLLIPGFFAR1DGAT1GSK3A
SCHEMBL31217318 0.82 LPL (0.48) LPLLIPGFFAR1DGAT1GSK3A
SCHEMBL31217371 0.82 LPL (0.48) LPLLIPGFFAR1DGAT1GSK3A
SCHEMBL31217322 0.81 LPL (0.37) LPLLIPGFFAR1DGAT1GSK3A
SCHEMBL31217373 0.81 LPL (0.38) LPLLIPGFFAR1DGAT1GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240368104-A1 Novel Dialkoxynaphtho[2,3-C]Furan-1(3H)-One Derivatives and Pharmaceutical Composition For Preventing or Treating Respiratory Disease or SARS-COV-2 Infection Disease, Comprising Same DONG WHA PHARM. CO., LTD. (KR) 2024-11-07 — — US disclosed
CN-109195965-B Inhibitors of WDR5 protein-protein binding 普罗佩纶治疗公司 2022-07-26 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368104-A1 Novel Dialkoxynaphtho[2,3-C]Furan-1(3H)-One Derivatives and Pharmaceutical Composition For Preventing or Treating Respiratory Disease or SARS-COV-2 Infection Disease, Comprising Same IL5, ACE2, IL15 LPL 3407/4885LIPG 3149/4885FFAR1 573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback