Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816545 | 1.00 | DHODH (0.58) | DHODH | |
| SCHEMBL20107945 | 1.00 | DHODH (0.58) | DHODH | |
| SCHEMBL21853478 | 0.84 | TSHR (0.43) | DHODH | |
| SCHEMBL29816442 | 0.84 | TSHR (0.43) | DHODH | |
| SCHEMBL20108091 | 0.84 | TSHR (0.43) | DHODH | |
| SCHEMBL20107955 | 0.82 | CNR2 (0.50) | DHODH | |
| SCHEMBL29816495 | 0.78 | DHODH (0.64) | DHODH | |
| SCHEMBL20107606 | 0.78 | DHODH (0.64) | DHODH | |
| SCHEMBL28823391 | 0.78 | DHODH (0.64) | DHODH | |
| SCHEMBL20107924 | 0.77 | DHODH (0.62) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557907-A | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | disclosed |