SCHEMBL2882358

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2881276	0.89	ROCK2 (0.71)	ROCK2CYP3A4OPRK1CDC7DAPK3
	Bay-549 SCHEMBL4765314	0.83	ROCK2 (1.00)	ROCK2CYP3A4OPRK1CDC7DAPK3
	Bay-549 SCHEMBL29431218	0.83	ROCK2 (1.00)	ROCK2CYP3A4OPRK1CDC7DAPK3
	Bay-549 SCHEMBL29783174	0.83	ROCK2 (1.00)	ROCK2CYP3A4OPRK1CDC7DAPK3
	SCHEMBL2885960	0.82	ROCK2 (0.63)	ROCK2CYP3A4OPRK1CDC7DAPK3
	SCHEMBL4406963	0.81	ROCK2 (0.65)	ROCK2CYP3A4OPRK1CDC7DAPK3
	SCHEMBL4772169	0.80	ROCK2 (1.00)	ROCK2CYP3A4OPRK1CDC7DAPK3
	SCHEMBL2881782	0.80	ROCK2 (0.45)	ROCK2CYP3A4OPRK1CDC7DAPK3
	SCHEMBL2886394	0.79	ROCK2 (0.60)	ROCK2CYP3A4OPRK1CDC7DAPK3
	Hydrochloric Acid SCHEMBL2887834	0.79	ROCK2 (0.44)	ROCK2CYP3A4OPRK1CDC7DAPK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.