Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 5/20 | 0.44 |
| ▸ | MGMT | P16455 | 4/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448639 | 0.85 | CDC7 (0.47) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL104931 | 0.84 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL29557469 | 0.84 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| Phosphoric Acid SCHEMBL27565804 | 0.80 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL288235 | 0.80 | ADORA1 (0.51) | BRAFDHFRADORA3ADORA2AADORA1 | |
| SCHEMBL28460506 | 0.78 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL13268695 | 0.77 | ENPP1 (0.46) | BRAFDHFRADORA3PDPK1GDA | |
| Adenine SCHEMBL7891002 | 0.77 | PI4KA (0.56) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL28104074 | 0.75 | PDPK1 (0.45) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30338256 | 0.75 | PDPK1 (0.42) | BRAFPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120137390-A1 | MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES | ARBORGEN INC. | 2012-05-31 | — | — | US | disclosed |
| EP-2427047-A2 | MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES | ArborGen Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129737-A2 | MATERIALS AND METHODS FOR REGENERATION AND TRANSFORMATION OF TREES | ARBORGEN, LLC (US) | 2010-11-11 | — | — | WO | disclosed |