Adenine

Adenine

SCHEMBL7891002

Nc1nc(Cc2ccccc2)nc2nc[nH]c12.Nc1ncnc2nc[nH]c12

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 5/20 0.56
PI4K2B Q8TCG2 5/20 0.56
PI4K2A Q9BTU6 5/20 0.56
PI4KB Q9UBF8 5/20 0.56
LMNA P02545 5/20 0.56
DRD3 P35462 1/20 0.56
XDH P47989 1/20 0.56
LRRK2 Q5S007 1/20 0.56
PDE4A P27815 1/20 0.56
PDE4B Q07343 1/20 0.56
PDE4C Q08493 1/20 0.56
PDE4D Q08499 1/20 0.56
CDC7 O00311 2/20 0.48
DBF4 Q9UBU7 2/20 0.48
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 2/20 0.47
TSHR P16473 2/20 0.47
CDK2 P24941 2/20 0.47
MAPK1 P28482 2/20 0.47
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL104931 0.92 PDE4A (0.64) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL29557469 0.92 PDE4A (0.64) PI4KAPI4K2BPI4K2API4KBLMNA
6-Benzylaminopurine SCHEMBL9474231 0.86 PDE4A (0.73) PI4KAPI4K2BPI4K2API4KBLMNA
Phosphoric Acid SCHEMBL27565804 0.85 PDE4A (0.56) LMNAPDE4APDE4BPDE4CPDE4D
Purine SCHEMBL9838579 0.84 PDE4A (0.51) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL27952435 0.81 LMNA (0.67) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL29241588 0.79 PDE4A (0.50) LMNAPDE4APDE4BPDE4CPDE4D
SCHEMBL28460506 0.78 PDE4A (0.48) LMNAPDE4APDE4BPDE4CPDE4D
SCHEMBL448639 0.77 CDC7 (0.47) LMNAPDE4APDE4BPDE4CPDE4D
SCHEMBL288236 0.77 BRAF (0.48) LMNAPDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001047360-A2 METHODS FOR TREATING PLANTS WITH CYCLIC GLYCOSIDES HAMPSHIRE CHEMICAL CORP. (US) 2001-07-05 WO disclosed