Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | HTT | P42858 | 6/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499597 | 0.99 | KDM4E (0.37) | KDM4EALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL28039878 | 0.89 | KDM4E (0.36) | KDM4EALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL28210142 | 0.88 | KDM4E (0.33) | KDM4EMAPTHTTLMNA | |
| SCHEMBL17499274 | 0.88 | KDM4E (0.37) | KDM4EALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL17499672 | 0.86 | KDM4E (0.33) | KDM4EMAPTHTTLMNA | |
| SCHEMBL28040283 | 0.86 | NR4A1 (0.43) | KDM4EALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16097217 | 0.84 | NR4A1 (0.44) | KDM4EALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16096661 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16096662 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL17499408 | 0.81 | GAA (0.35) | KDM4EALDH1A1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209268-A | Heterocyclic imine functionalized polymers | BRIDGESTONE CORP | 2015-12-30 | — | — | CN | disclosed |