SCHEMBL17499672

SCHEMBL17499672

Cc1ccc(O[SiH](C)C)c(N=Cc2ncncn2)c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28210142 0.99 KDM4E (0.33) KDM4ELMNAMAPTHTT
SCHEMBL17499646 0.89 KDM4E (0.31) KDM4ELMNAMAPTHTT
SCHEMBL17499597 0.88 KDM4E (0.37) KDM4ELMNAMAPTHTT
SCHEMBL28823604 0.86 KDM4E (0.36) KDM4ELMNAMAPTHTT
SCHEMBL16101193 0.85 ACHE (0.41) KDM4ELMNAMAPTHTT
SCHEMBL16101192 0.85 ACHE (0.41) KDM4ELMNAMAPTHTT
SCHEMBL17499812 0.82 KDM4E (0.34) KDM4ELMNAMAPTHTT
SCHEMBL17499816 0.82 KDM4E (0.34) KDM4ELMNAMAPTHTT
SCHEMBL17499722 0.82 KDM4E (0.30) KDM4E
SCHEMBL17499634 0.78 KDM4E (0.36) KDM4ELMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed