SCHEMBL28823940

SCHEMBL28823940

C(OCC1CO1)C1CO1.Cc1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.41
ALOX15 P16050 3/20 0.41
TYR P14679 2/20 0.41
NR1I2 O75469 1/20 0.41
LMNA P02545 1/20 0.41
CYP2C9 P11712 1/20 0.41
MIF P14174 1/20 0.41
HTT P42858 1/20 0.41
NFE2L2 Q16236 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TSHR P16473 6/20 0.40
MAPK1 P28482 2/20 0.40
ATM Q13315 1/20 0.37
TP53 P04637 5/20 0.37
MAPT P10636 3/20 0.37
HIF1A Q16665 3/20 0.37
HPGD P15428 2/20 0.37
CYP1A2 P05177 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28223415 0.90 TSHR (0.41) ALDH1A1ALOX15TYRCYP2C9HTT
E319 SCHEMBL1354704 0.87 ALDH1A1 (0.59) ALDH1A1ALOX15TYRNR1I2LMNA
SCHEMBL1356634 0.85 ALDH1A1 (0.52) ALDH1A1ALOX15TYRNR1I2LMNA
SCHEMBL3106376 0.84 TSHR (0.56) ALDH1A1TSHRMAPK1TP53MAPT
SCHEMBL28042537 0.83 TP53 (0.57) ALDH1A1ALOX15LMNAHSD17B10TSHR
SCHEMBL27934586 0.78 PPARG (0.49) LMNAHTTPPARGPOLBCYP3A4
SCHEMBL23389375 0.78 HSPA5 (0.65) ALDH1A1TYRLMNACYP2C9HSD17B10
SCHEMBL270433 0.78 ALDH1A1 (0.64) ALDH1A1ALOX15TYRNR1I2LMNA
SCHEMBL29359626 0.78 ALDH1A1 (0.64) ALDH1A1ALOX15TYRNR1I2LMNA
SCHEMBL10903097 0.77 ESR1 (0.61) ALDH1A1ALOX15TSHRMAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929773-A Two-part epoxy composition for adhesive coating of storage articles SWIMC有限公司 2022-08-19 CN claimed