SCHEMBL28823992

SCHEMBL28823992

CC(C#N)C(=O)/N=C/N(C)C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.31
ALOX15 P16050 1/20 0.31
HTT P42858 1/20 0.31
PTK2B Q14289 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28823993 1.00 ALDH1A1 (0.34) ALDH1A1TP53ALOX15HTTPTK2B
SCHEMBL12200032 0.76 CYP1A2 (0.31)
SCHEMBL2275997 0.76 CYP1A2 (0.31)
SCHEMBL2275993 0.76 CYP1A2 (0.31)
SCHEMBL28928422 0.74 TP53 (0.33) TP53
SCHEMBL23301101 0.72
SCHEMBL21857857 0.72
SCHEMBL28890358 0.72 CYP1A2 (0.31)
SCHEMBL20899842 0.70 POLB (0.33)
SCHEMBL20899843 0.70 POLB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957234-A Triazole-containing phenyloxadiazole derivative and preparation method and application thereof 浙江工业大学 2022-08-30 CN disclosed