Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1324662 | 0.86 | NPSR1 (0.47) | NPSR1S1PR4KDM4EPKMRCE1 | |
| SCHEMBL28287874 | 0.85 | NPSR1 (0.50) | NPSR1S1PR4KDM4EPKMRCE1 | |
| SCHEMBL31214355 | 0.84 | NPSR1 (0.45) | NPSR1S1PR4KDM4EPKMRCE1 | |
| SCHEMBL31586748 | 0.83 | NPSR1 (0.44) | NPSR1S1PR4KDM4EPKMRCE1 | |
| SCHEMBL31586538 | 0.83 | NPSR1 (0.44) | NPSR1S1PR4KDM4EPKMRCE1 | |
| SCHEMBL14152137 | 0.83 | NPSR1 (0.44) | NPSR1S1PR4KDM4EPKMRCE1 | |
| SCHEMBL17144460 | 0.81 | PDK2 (0.40) | NPSR1S1PR4KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL23628471 | 0.81 | NQO2 (0.47) | NPSR1S1PR4KDM4EPKMRCE1 | |
| SCHEMBL28043598 | 0.81 | NPSR1 (0.45) | NPSR1S1PR4KDM4EPKMRCE1 | |
| SCHEMBL22445783 | 0.80 | CYP1A2 (0.47) | NPSR1S1PR4KDM4EPKMRCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377830-A | 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic) pyrimidine-4-carboxylates and their use as herbicides | DOW AGROSCIENCES LLC | 2016-03-02 | — | — | CN | disclosed |
| CN-105209452-A | 4-amino-6- (heterocyclyl) pyridine-2-carboxylic acid esters and 6-amino-2- (heterocyclyl) pyrimidine-4-carboxylic acid esters and their use as herbicides | DOW AGROSCIENCES LLC | 2015-12-30 | — | — | CN | disclosed |
| CN-105209451-A | 4-amino-6- (heterocyclyl) pyridine-2-carboxylic acid esters and 6-amino-2-2 (heterocyclyl) pyrimidine-4-carboxylic acid esters and their use as herbicides | DOW AGROSCIENCES LLC | 2015-12-30 | — | — | CN | disclosed |