Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAUR | Q03405 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824031 | 0.91 | PLAUR (0.38) | PLAURKDRHSP90AA1NPC1NFKB1 | |
| SCHEMBL28824104 | 0.83 | MAPK10 (0.47) | HSP90AA1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL28949291 | 0.82 | KMO (0.42) | MAPK9MAPK10CA9PTGS2ALDH1A1 | |
| SCHEMBL28824080 | 0.81 | NPC1 (0.40) | HSP90AA1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL28824139 | 0.80 | PTGDR2 (0.42) | KDRHSP90AA1NPC1NFKB1RAB9A | |
| SCHEMBL28823986 | 0.79 | FOLH1 (0.44) | HSP90AA1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL28949290 | 0.78 | DHODH (0.46) | HSP90AA1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL28824033 | 0.78 | PTGS1 (0.42) | HSP90AA1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL28824039 | 0.78 | CA1 (0.44) | HSP90AA1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL28824007 | 0.78 | NPC1 (0.39) | HSP90AA1NPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |