Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257406 | 0.98 | ACHE (0.52) | ACHEACP3ALDH1A1MAPK1AOC3 | |
| SCHEMBL12329329 | 0.86 | ACHE (0.50) | ACHEACP3ALDH1A1MAPK1AOC3 | |
| SCHEMBL10797679 | 0.80 | ACHE (0.55) | ACHEACP3ALDH1A1MAPK1AOC3 | |
| SCHEMBL29352930 | 0.80 | ACHE (0.55) | ACHEACP3ALDH1A1MAPK1AOC3 | |
| SCHEMBL931982 | 0.80 | ACHE (0.55) | ACHEACP3ALDH1A1MAPK1AOC3 | |
| SCHEMBL99347 | 0.80 | ACHE (0.55) | ACHEACP3ALDH1A1MAPK1AOC3 | |
| SCHEMBL5490186 | 0.80 | ACHE (0.55) | ACHEACP3ALDH1A1MAPK1AOC3 | |
| SCHEMBL29378635 | 0.80 | ACHE (0.55) | ACHEACP3ALDH1A1MAPK1AOC3 | |
| SCHEMBL23183184 | 0.79 | ACHE (0.48) | ACHEACP3ALDH1A1MAPK1AOC3 | |
| SCHEMBL27897336 | 0.79 | ACHE (0.48) | ACHEACP3ALDH1A1MAPK1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805161-B | Preparation method of 3-fluolobidine hydrochloride | 南通华祥医药科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-114805161-A | Preparation method of 3-fluridinyl hydrochloride | 南通华祥医药科技有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-117957235-A | Synthesis of fluoroalkyl tin precursors | 恩特格里斯公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-114805161-B | Preparation method of 3-fluolobidine hydrochloride | 南通华祥医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-114805161-B | Preparation method of 3-fluolobidine hydrochloride | 南通华祥医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-114805161-A | Preparation method of 3-fluridinyl hydrochloride | 南通华祥医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805161-A | Preparation method of 3-fluridinyl hydrochloride | 南通华祥医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |