Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25971992 | 0.84 | HSD17B10 (0.40) | HCAR2HPGDMEN1KMT2A | |
| SCHEMBL6006960 | 0.72 | MAPT (0.44) | HCAR2MAPTHCAR3 | |
| SCHEMBL19224520 | 0.69 | NR1H2 (0.56) | HCAR2 | |
| SCHEMBL7654678 | 0.69 | GLA (0.45) | GLAMAPTHPGDMEN1KMT2A | |
| SCHEMBL26111742 | 0.69 | GLA (0.45) | GLAMAPTHPGDMEN1KMT2A | |
| SCHEMBL8656383 | 0.69 | — | — | |
| SCHEMBL6771598 | 0.69 | — | — | |
| SCHEMBL25971994 | 0.68 | TP53 (0.39) | HCAR2MAPTHPGDMEN1KMT2A | |
| SCHEMBL6007194 | 0.68 | ALDH1A1 (0.42) | HCAR2MAPTHCAR3HPGDMEN1 | |
| SCHEMBL27146220 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103073513-B | 1-replaces the chloro-2H-1 of-5-, 2,3-triazole-4-carboxylic acid derivative and preparation method thereof | ABA CHEMICALS CORPORATION (CN) | 2015-12-02 | — | — | CN | disclosed |