Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139343 | 0.81 | ADRB2 (0.41) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL2139328 | 0.81 | ADRB2 (0.41) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL10241878 | 0.76 | ADRB2 (0.48) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL2142861 | 0.74 | CHRM2 (0.40) | CHRM3CHRM2 | |
| SCHEMBL2142872 | 0.71 | ADRB2 (0.35) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL2138554 | 0.71 | CHRM3 (0.44) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL2138543 | 0.71 | CHRM3 (0.44) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL2142928 | 0.67 | ADRB2 (0.47) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL10241726 | 0.67 | ADRB2 (0.47) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL10241540 | 0.66 | ADRB2 (0.55) | ADRB2CHRM3ADRB1DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-A1 | COMPOUNDS | AstraZeneca AB (SE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009098448-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | WO | disclosed |