SCHEMBL28824907

SCHEMBL28824907

Fc1ccc(-n2cnc3ccccc32)cc1

nearest known ligand 0.72

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.72
FGFR1 P11362 4/20 0.69
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
MAPT P10636 1/20 0.52
KMT2A Q03164 1/20 0.52
PTK2B Q14289 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3419279 0.90 HTT (0.88) HTTFGFR1KDM4EALDH1A1RAB9A
SCHEMBL30402227 0.90 HTT (0.88) HTTFGFR1KDM4EALDH1A1RAB9A
SCHEMBL2531256 0.85 HTT (0.78) HTTFGFR1KDM4EALDH1A1RAB9A
SCHEMBL157265 0.84 HTT (1.00) HTTFGFR1
Benzene SCHEMBL14876970 0.84 HTT (1.00) HTTFGFR1
SCHEMBL5246440 0.83 HTT (0.75) HTTFGFR1KDM4EALDH1A1RAB9A
SCHEMBL4891428 0.82 HTT (0.96) HTTFGFR1
SCHEMBL467858 0.82 HTT (0.96) HTTFGFR1
Iodide SCHEMBL30645138 0.82 HTT (0.96) HTTFGFR1
SCHEMBL30723122 0.82 HTT (0.68) HTTFGFR1KDM4EALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119118844-A Method for preparing N-phenyl phenylenediamine compound by structural reforming of imidazole compound 中国科学院兰州化学物理研究所 2024-12-13 CN disclosed
CN-114989094-B Method for synthesizing benzimidazole derivative by visible light catalysis 云南民族大学 2023-09-29 CN disclosed
CN-114989094-A Method for synthesizing benzimidazole derivative by visible light catalysis 云南民族大学 2022-09-02 CN disclosed