Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825520 | 0.90 | GRIN2B (0.53) | KCNH2GRIN2BPDE4BGRIN1 | |
| SCHEMBL28825491 | 0.89 | PDE4B (0.49) | KCNH2GRIN2BPDE4BGRIN1 | |
| SCHEMBL28825479 | 0.89 | KCNH2 (0.49) | KCNH2GRIN2BPDE4BGRIN1 | |
| SCHEMBL28825540 | 0.89 | KCNH2 (0.49) | KCNH2GRIN2BPDE4BGRIN1 | |
| SCHEMBL28825466 | 0.87 | GRIN2B (0.44) | KCNH2GRIN2BPDE4BGRIN1 | |
| SCHEMBL28825559 | 0.87 | PDE4B (0.48) | GRIN2BPDE4BGRIN1 | |
| SCHEMBL28825511 | 0.84 | PDE4B (0.48) | KCNH2GRIN2BPDE4BGRIN1 | |
| SCHEMBL28694731 | 0.81 | GRIN2B (0.43) | KCNH2GRIN2BPDE4BGRIN1 | |
| SCHEMBL28949563 | 0.81 | PDE4B (0.46) | GRIN2BPDE4BGRIN1 | |
| SCHEMBL28964549 | 0.80 | GAA (0.43) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |