Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 13/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825540 | 0.93 | KCNH2 (0.49) | GRIN2BKCNH2GRIN1PDE4BGAA | |
| SCHEMBL28825479 | 0.91 | KCNH2 (0.49) | GRIN2BKCNH2GRIN1PDE4B | |
| SCHEMBL28825485 | 0.90 | KCNH2 (0.48) | GRIN2BKCNH2GRIN1PDE4B | |
| SCHEMBL28949576 | 0.83 | KCNH2 (0.49) | GRIN2BKCNH2GRIN1PDE4B | |
| SCHEMBL28825492 | 0.80 | KCNH2 (0.48) | GRIN2BKCNH2GRIN1PDE4B | |
| SCHEMBL28825491 | 0.79 | PDE4B (0.49) | GRIN2BKCNH2GRIN1PDE4B | |
| SCHEMBL28825550 | 0.78 | GAA (0.45) | GRIN2BKCNH2GRIN1PDE4BGAA | |
| SCHEMBL28825442 | 0.76 | PDE4B (0.55) | GRIN2BKCNH2GRIN1PDE4BGAA | |
| SCHEMBL28825588 | 0.76 | GAA (0.50) | GRIN2BKCNH2GRIN1PDE4BGAA | |
| SCHEMBL28825559 | 0.75 | PDE4B (0.48) | GRIN2BGRIN1PDE4BGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |